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Rami N. Khayat, MD


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473 W 12th Ave
Columbus, OH 43210

Phone: (614) 293-4925

Email: khayat.3@osu.edu

 

Current OSU Appointments

Associate Professor-Clinical, Pulm,Allergy,Crit Care & Sleep

Physician, FGP-Pulm-Allrgy-CritCare-Sleep

 

Clinical Interest

Sleep medicine and critical care medicine

Continuing Education, Extension, and Other Courses Taught

Continuing Medical Education:



Sleep disordered breathing and cardiovascular disease:



Invitations to present in national and international venues have increased since 2010. I recently presented in the international Heart Failure Society of America in 2013; and was invited to be the key note speaker in a conference in Japan in 2013. Other invitations are listed in the relevant “invited presentations” section and include speaking in major academic centers in the US. I was invited to lead a thematic poster session in the American Thoracic Society in May 2015.



Sleep Heart fellowship (2009-2013):

This is a novel educational program targets cardiologists, sleep specialists, clinicians in the area of sleep medicine and heart failure, along with sleep laboratory technicians and administrators. The mission of this program is to disseminate knowledge of the cardiovascular consequences of sleep disordered breathing; educate practitioners about the new methods, algorithms, and technologies in diagnosis and treatment of sleep disordered breathing in this unique population. This fellowship disseminates to clinicians and leaders in the area of cardiology and sleep medicine the novel care algorithms developed in the Sleep Heart Program. the fellowship was offered through 2013 and was halted, despite increased interest, due to my clinical time commitment



Other relevant CME symposia and conferences with major involvement:

Selected CME areas and activities and invitations to speak in corresponding national venues are listed separately in the “Invited Presentations” section.

Academic Advising

Undergraduate:



Diane Haddad (undergraduate): Molecular Genetics major; Diane graduated with Honors in Research; I supervised her Research thesis. She presented two abstracts and won the Davis Heart and Lung Research Institute Student Research Award (2012). She attended Boston University Medical School in 2013.



Jacob Wannemacher: Biology major; He graduated and was accepted to the OSU Medical School (2012). he was an author on 2 manuscripts presented nationally and internationally (Heart failure Society of America International Conference).



Robert Dohar: OSU Bilogy major; graduated and accepted into Medical School at Northeast Ohio Medical University (2015). He is an author on two published manuscripts.



Masters:

Monica Roy,MPH: I advised Monica between 2004-2006. I supervised an independent study course in Public Health. I mentored here in preparing and presenting an abstract in a national meeting (American Thoracic Society), and subsequently in becoming a co-author in a peer reviewed publication (Chest journal). Monica graduated from the Optometry School at OSU and joined the faculty.



Michael Powers (2004-2006): MPH student; Michael co-authored a peer reviewed article, won a research travel award and I served as an overall career adviser for Michael. Additionally,he published one manuscript as a first author. He graduated from Medical School at the University of Chicago in 2010.



Raymond Pongonis II: Pogie co-authored a peer review article under my supervision. He was accepted for Internal Medicine residency in 2007 at Northwestern University.



Brian Patt, Masters of Biostatistics: I mentored Brian 2008-2012. Brian successfully presented 4 abstracts in national and international meetings. He won a regional award for a poster presentation in October/2008. he has given several national and international presentations and co-authored several peer reviewed papers (see publications).





Ph.D student:

Robin Trupp: Robin performed the research for her thesis under my supervision. She submitted a manuscript of her findings and already has several peer reviewed articles. She is a recognized leader of nursing education and a national leader in heart failure advanced nurse practitioner organizations; She is a faculty member at Duke University.



Fellow:

1- Kiran Devulapaly: Author of a peer review article



2- Meena Khan: I supervised her training in sleep medicine (with the program director); she is current faculty member and I continue to advise her



3- Troy Schaffernocker: I supervised his training in sleep medicine, he is currently a faculty member at OSU. He published several articles with me.



4- Donald Kikta, Fellow, Jan 2010 - Jun 2012. Presenter at a regional, national, or international conference, Author or co-author of a published paper, Heart Failure



5- Jarrod Bruce: He authored presented two abstracts in international meetings. currently in private practice but continuing to contribute to a manuscript.



6- Adam Pleister: He concludes his Sleep fellowship in June 2015. He authored several (see publications) manuscripts with me and presented two abstracts. He will be a faculty member in the Cardiology division. Adam is one of few Heart Failure specialists in the US who will be board eligible for Sleep Medicine.

Advising Narrative

Several students presented in national and international conferences and co-authored papers. Each student accomplishment is detailed in the related list of students.

Academic Advising

2007 - present Brian Patt The Ohio State University.
2008 - present Qihui Liu The Ohio State University.
2011 - present Robert Dohar The Ohio State University.
2011 - present Saradhadevi Varadharaj The Ohio State University.
2014 - present Adam Pleister, The Ohio State University.
2006 - 2008 Monica The Ohio State University.
2007 - 2008 Meena Khan The Ohio State University.
2007 - 2008 Robin Trupp The Ohio State University. Graduated 2008.
2007 - 2008 Kiran Devulapaly The Ohio State University.
2007 - 2008 Troy Schaffernocker The Ohio State University.
2006 - 2009 Michael Powers The Ohio State University.
2007 - 2009 Raymond Pongonis The Ohio State University.
2007 - 2009 Joshua Gestosani The Ohio State University.
2008 - 2009 Meena Khan The Ohio State University.
2007 - 2010 Diane Haddad The Ohio State University.
2009 - 2011 Jarrod Bruce The Ohio State University. Graduated 2012.
2010 - 2011 Jenny Hessieh The Ohio State University.
2008 - 2012 Jacob Wannemacher The Ohio State University. Graduated 2012.
2010 - 2012 Donald Kikta The Ohio State University. Graduated 2012.
 

Certifications

1999 - present Board Certification: American Board of Internal Medicine
2003 - present Medical License: State Medical Board of Ohio
2004 - present Board Certification: American Board of Sleep Medicine
2009 - present Board Recertification: American Board of Medical Specialties
2011 - present Board Recertification: American Board of Internal Medicine
2012 - present Board Recertification: American Board of Internal Medicine
2002 - 2011 Board Certification: American Board of Internal Medicine
2003 - 2012 Board Certification: American Board of Internal Medicine
 

Chapters in Books

Rami Khayat, Ulysses J. Magalang, Naeem Ali. "Monitoring Respiration During Sleep." In Sleep: A comprehensive handbook. Edited by Teofilo L. Lee-Chiong. 1025-1030. Denver: 2006 John Wiley & Sons, Inc, January 2005.

Rami Khayat and William Abraham. "Sleep related Breathing Disorders in the Acute Heart Failure Syndrome." In The Acute Heart Failure Syndrome. Edited by Alexander Mebazaa Joseph Perrillo. -. The Guildway, Old Portsmouth Road Guildford, GU3 1LP, UK: Springer-Verlag London Ltd Ashbourne House, January 2007.

Schaffernocker T, Khayat RN. "Sleep Apnea and Heart Failure." In Heart Failure: Principles and Clinical Management. -. New York, NY, US|USA: McGraw Hill, January 2011.

 

Clinical Services

01/01/2004 OSUE inpatient service (OSUE hospital)
01/01/2004 Pulmonary and Critical Care inpatient service (OSUMC, Internal Medicine)
01/01/2004 - 10/01/2009 Outpatient Sleep Medicine clinics and test interpretation (OSUE hospital; Ross heart hospital; Martha Morehouse Medical Plaza, Internal medicine)

Degrees

1988 None Indicated, National Orthodox College

1994 M.D., Tishreen University

 

Editorial Activities

2006 - present Lung
2006 - 2008 Journal of Cardiac Failure
2007 - present European Heart Journal
2007 International Journal of COPD
2007 - 2008 Heart Failure Reviews
2008 Antioxidants & Redox Signaling
2008 Journal of Respiratory Diseases
2009 - present Journal of the American College of Cardiology (JACC)
2010 - present Population Health Science and Health Service Research; Republic of Ireland
2010 - present International Journal of Cardiology
2012 - present Chest
2014 - present UpToDate; Sleep Medicine Section
2014 - present Sleep and Breathing
2015 - present Chest
 

Honors

1988 - present Honor List. Lattakia Directorship of Education.
1989 - present Recognition of Outstanding Academic Achievement and Scholarship. The Roman Orthodox Archdiocese, Lattakia, Syria.
1989 - 1996 Dean's List. Tishreen University Faculty of Medicine, Lattakia, Syria.
1994 - present Rating of Excellence. Tishreen University-Faculty of Medicine.
1999 - present Resident Evaluation Committee Recognition. Department of Medicine.
2002 - 2003 National Research Service Award. National Heart, Lung, and Blood Institute.
2009 - present The OSU-Davis Bremer and NIH Center for Clinical and Translational Science (CCTS) at OSU (CCTS) Award. OSU.
 

Journal Articles

Khayat,R,N; Xie,A,L; Patel,A,K; Kaminski,A; Skatrud,J,B. "Cardiorespiratory effects of added dead space in patients with heart failure and central sleep apnea." Chest. Vol. 123, no. 5. (January 2003.): 1551-60.

LeMarbre,G; Stauber,S; Khayat,R,N; Puleo,D,S; Skatrud,J,B; Morgan,B,J. "Baroreflex-induced sympathetic activation does not alter cerebrovascular CO2 responsiveness in humans.." The Journal of Physiology. Vol. 551, no. Pt 2. (January 2003.): 609-16.

Khayat,R,N; Przybylowski,T; Meyer,K,C; Skatrud,J,B; Morgan,B,J. "Role of sensory input from the lungs in control of muscle sympathetic nerve activity during and after apnea in humans." Journal of Applied Physiology (Bethesda, Md. : 1985). Vol. 97, no. 2. (January 2004.): 635-40.

Xie,A,L; Skatrud,J,B; Khayat,R; Dempsey,J,A; Morgan,B; Russell,D. "Cerebrovascular response to carbon dioxide in patients with congestive heart failure.." American Journal of Respiratory and Critical Care Medicine. Vol. 172, no. 3. (January 2005.): 371-8.

Xie,Ailiang; Skatrud,James,B; Morgan,Barbara; Chenuel,Bruno; Khayat,Rami; Reichmuth,Kevin; Lin,Jenny; Dempsey,Jerome,A. "Influence of cerebrovascular function on the hypercapnic ventilatory response in healthy humans." The Journal of Physiology. Vol. 577, no. Pt 1. (January 2006.): 319-29.

Valdivia-Arenas, Martin, A; Khayat, Rami. "An asian woman with eosinophilia and bilateral pulmonary infiltrates." Respiration: International Review of Thoracic Diseases. Vol. 74, no. 2. (January 2007.): 224-7.

Khayat,Rami,N; Abraham,William,T; Patt,Brian; Roy,Monica; Hua,Keding; Jarjoura,David. "Cardiac Effects of Continuous and Bi-level Positive Airway Pressure for Patients with Heart Failure and Obstructive Sleep Apnea: A Pilot Study." Chest. Vol. 6, no. 134. (July 2008.): 1162-8.

Devulapally K, Pongonis R Jr, Khayat R.. "OSA: the new cardiovascular disease : Part II: overview of cardiovascular diseases associated with obstructive sleep apnea.." Heart failure Reviews. no. Epub-ahead of publication. (August 2008.): -.

Valdivia-Arenas,Martin,A; Powers,Michael; Khayat,Rami,N. "Sleep-disordered breathing in patients with decompensated heart failure." Heart Failure Reviews. Vol. 3, no. 14. (August 2008.): 183-193.

Rami Khayat, MD, Brian Patt, BS, and Don Hayes, Jr., MD. "Obstructive Sleep Apnea and the Pathogenesis of Vascular Disease." Heart Failure Reviews. Vol. Sep; 14 (2), no. 14:9112. (August 2008.): 143-53.

Devulapally,Kiran; Pongonis,Raymond; Khayat,Rami. "OSA: the new cardiovascular disease." HEART FAILURE REVIEWS. Vol. 14, no. 3. (September 2009.): 155-164.

Khayat,Rami,N; Abraham,William,T; Patt,Brian; Pu,Min; Jarjoura,David. "In-hospital Treatment of Obstructive Sleep Apnea During Decompensation of Heart Failure." Chest. Vol. 4, no. 136. (October 2009.): 991-997.

Khayat,Rami; Patt,Brian; Hayes,Don. "Obstructive sleep apnea: the new cardiovascular disease. Part I: obstructive sleep apnea and the pathogenesis of vascular disease." HEART FAILURE REVIEWS. Vol. 14, no. 3. (September 2009.): 143-153.

Khayat,Rami,N; Jarjoura,David; Patt,Brian; Yamokoski,Todd; Abraham,William,T. "In-hospital Testing for Sleep Disordered Breathing in Hospitalized Patients with Decompensated Heart Failure: Report of Prevalence and Patient Characteristics." Journal of Cardiac Failure. Vol. 9, no. 15. (January 2009.): 739-746.

Rami N Khayat, Andrew Pederzolli, William T. Abraham. "Central Sleep Apnea and Heart Failure." U.S. Cardiology (quarterly). Vol. /, (September 2009.): .-.

Aneesa M Das, Rami Khayat. "Hypertension in Obstructive Sleep Apnea: Risk and Therapy." Expert Reviews. Vol. 7, no. 6. (June 2009.): 619-626.

Patt,Brian,T; Jarjoura,David; Haddad,Diane,N; Sen,Chandan,K; Roy,Sashwati; Flavahan,Nicholas,A; Khayat,Rami,N. "Endothelial Dysfunction in the Microcirculation of Patients with Obstructive Sleep Apnea." American Journal of Respiratory and Critical Care Medicine. Vol. 12, no. 182. (July 2010.): 1540-1545.

Patt,Brian,T; Jarjoura,David; Lambert,Lynn; Roy,Sashwati; Gordillo,Gayle; Schlanger,Richard; Sen,Chandan,K; Khayat,Rami,N. "Prevalence of Obstructive Sleep Apnea in Patients with Chronic Wounds." Journal of Clinical Sleep Medicine. Vol. 6, no. 6. (December 2010.): 541-545.

Ponikowski,Piotr; Javaheri,Shahrokh; Michalkiewicz,Dariusz; Bart,Bradley,A; Czarnecka,Danuta; Jastrzebski,Marek; Kusiak,Aleksander; Augostini,Ralph; Jagielski,Dariusz; Witkowski,Tomasz; Khayat,Rami,N; Oldenburg,Olaf; Gutleben,Klaus-Juergen; Bitter,Thomas; Karim,Rehan; Iber,Conn; Hasan,Ayesha; Hibler,Karl; Germany,Robin; Abraham,William,T. "Transvenous Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea in Heart Failure." European Heart Journal. Vol. Apr;33(7), (August 2011.): 889-94.

Kahwash R, Kikta D, Khayat RN. "Recognition and Management of Sleep-Disordered Breathing in Chronic Heart Failure." Current Heart Failure Reports. Vol. 1, no. 8. (March 2011.): 72-79.

Javaheri,Shahrokh; Goetting,Mark,G; Khayat,Rami; Wylie,Paul,E; Goodwin,James,L; Parthasarathy,Sairam. "The performance of two automatic servo-ventilation devices in the treatment of central sleep apnea." Sleep. Vol. 1;34(12): doi: 10.5665/sleep.1438., (December 2011.): 1693-8.

Varadharaj,Saradhadevi; Wannemacher,Jacob; Patt,Brian; Reyes,Levy; Jay,Zweier,L; Khayat,Rami. "eNOS Uncoupling Leads to Endothelial Dysfunction in Clinical Obstructive Sleep Apnea (OSA): Role of BH4 Depletion." CIRCULATION. Vol. 126, no. 21. (November 2012.): /-.

Varadharaj,Saradhadevi; Wannemacher,Jacob; Patt,Brian; Rao,Hemalatha; Reyes,Levy; Khayat,Rami; Zweier,Jay,L. "S-glutathionylation of eNOS occurs in Clinical Obstructive Sleep Apnea (OSA)." CIRCULATION. Vol. 126, no. 21. (November 2012.): /-.

Schaffernocker, T, Khayat, RN. "Management of Central Sleep Apnea." US Cardiology. Vol. ., (December 2012.): /-.

Khayat,Rami; Abraham,William; Patt,Brian; Brinkman,Vincent; Wannemacher,Jacob; Porter,Kyle; Jarjoura,David. "Central Sleep Apnea is a Predictor of Cardiac Readmission in Hospitalized Patients With Systolic Heart Failure." JOURNAL OF CARDIAC FAILURE. Vol. 18, no. 7. (July 2012.): 534-540.

Troy Schaffernocker and Rami Khayat. "Management of Central Sleep Apnea." U.S Cardiology. Vol. 2012;9(1), (January 2012.): online Journal-.

Campbell L, Best J, Khayat R, Splaingard M. "Issues applying a math model to estimate continuous positive airway pressure response in Cheyne-Stokes respiration.." Am J Respir Crit Care Med.. Vol. 1;187(5):553., (March 2013.): 553-.

Rami Khayat, MD, Roy Small, MD, Lisa Rathman, MSN, CRNP, Steven Krueger, MD, Becky Gocke, RN, Linda Clark, RN, Laura Yamokoski, RN, William T. Abraham, MD. "Sleep-Disordered Breathing in Heart Failure: Identifying and Treating an Important but Often Unrecognized Comorbidity in Heart Failure Patients." Journal of Cardiac Failure. Vol. Volume 19,, no. Issue 6. (June 2013.): Pages 431–444-.

Sow,Angela; Dohar,Robert; Mantia,Brittany; Lahman,Matthew; Abraham,William; Khayat,Rami. "Sleep Disordered Breathing Is an Independent Predictor of One Month Readmission in Decompensated Heart Failure Hospitalizations." JOURNAL OF CARDIAC FAILURE. Vol. 19, no. 8. (August 2013.): S26-S27.

Sow,Angela; Dohar,Robert; Mantia,Brittany; Lahman,Matthew; Abraham,William; Khayat,Rami. "Sleep Disordered Breathing as an Independent Predictor of Post-Discharge Mortality in Patients with Acutely Decompensated Heart Failure." JOURNAL OF CARDIAC FAILURE. Vol. 19, no. 8. (August 2013.): S4-S4.

Ponikowski,Piotr; Ponikowski,Piotr; Jagielski,Dariusz; Oldenburg,Olaf; Augostini,Ralph; Krueger,Steven; Kolodziej,Adam; Gutleben,Klaus-Jurgen; Khayat,Rami; Merliss,Andrew; Javaheri,Shahrokh; Abraham,William. "Transvenous Phrenic Nerve Stimulation in the Treatment of Central Sleep Apnea in Patients with Reduced Ejection Fraction: A Report from the remede (R) System Pilot Study." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Vol. 62, no. 18. (October 2013.): B43-B43.

Das, A, Kahwash, R, Khayat, RN. "The Current Management of Patients with Syndromes Associated with Obstructive and Central Apnea." Journal Minerva Pneumologica. Vol. 3, (July 2014.): /-.

Pleister,Adam; Hasan,Ayesha; Abraham,William,T; James,Kristofer; Khayat,Rami. "Changes in Thoracic Impedance Measured via the Azygos Vein with the remede (R) System Indicate Worsening Heart Failure." JOURNAL OF CARDIAC FAILURE. Vol. 20, no. 8. (August 2014.): S111-S112.

Schaffernocker, T, Morrison, J, Khayat, RN. "Central Sleep Apnea: From Pathophyiology to Clinical Management." World Journal of Cardiovascular Diseases. Vol. ., (January 2014.): /-.

Oza,Nishaki; Baveja,Swati; Khayat,Rami; Houmsse,Mahmoud. "Obstructive sleep apnea and atrial fibrillation: understanding the connection.." Expert review of cardiovascular therapy. Vol. 12, no. 5. (May 2014.): 613-621.

Pleister, A, Khayat, RN. "Cardiovascular Disorders and Sleep Apnea- What's on the Horizon." Current Respiratory Care Reports (indexed). Vol. /, (January 2015.): .-.

Abraham, WT, Jagielski, D, Oldenburg, O, Augostini, R, Krueger, S, Kolodziej, A, Gutleben, KJ, Khayat, R, Merliss, A, Harsch, M, Holcomb, R, Javaheri, S, Ponikowski, P. "Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea." J Am Coll Cardiol HF. Vol. 10, (May 2015.): 360-9.

Varadharaj,Saradhadevi; Porter,Kyle; Pleister,Adam; Wannemacher,Jacob; Sow,Angela; Jarjoura,David; Zweier,Jay,L; Khayat,Rami,N. "Endothelial nitric oxide synthase uncoupling: A novel pathway in OSA induced vascular endothelial dysfunction." RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY. Vol. 207, (February 2015.): 40-47.

Khayat, RN, Jarjoura, D, Wannemacher, J, Porter, K, Sow, A, Dohar, R, Pleister, A, Abraham, WT. "Sleep Disordered Breathing and Post-Discharge Mortality in Patients with Heart Failure." Eur Heart J. Vol. 2015 Jan 29. pii: ehu522., (January 2015.): 2015 Jan 29. pii: ehu522. [Epub ahead of print] Impact factor 14.73-.

Costanzo,Maria,Rosa; Khayat,Rami; Ponikowski,Piotr; Augostini,Ralph; Stellbrink,Christoph; Mianulli,Marcus; Abraham,William,T. "Mechanisms and Clinical Consequences of Untreated Central Sleep Apnea in Heart Failure." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Vol. 65, no. 1. (January 2015.): 72-84.

Kemper, K, Mo, Xiaokui, Khayat, RN.. ""Do Mindfulness and Self-Compassion Predict Sleep and Resilience in Health Professionals? (JACM-2014-0281)." Jan 2015." Jounral of Alternative and Complimentary Medicine (JACM). -.

 

Reference Works

January 1999 Rami N. Khayat, Daling Zhu, and Elizabeth RJacobs."Chronic hypoxia induces epoxyeicosatrienoic acids (EETS) in neonatal rabbit lungs" /.
January 2002 Rami N. Khayat, MD, Ailiang Xie PhD, and James Skatrud, MD."The ventilatory and cardiovascular effects of dead space in patients with CHF-CSA" /.
January 2003 Rami N. Khayat, Barbara Morgan, James Skatrud, and Jerry Dempsey."The role of pulmonary stretch reflex in neurocirculatory response to apnea" ..
January 2003 Xie, R.N. Khayat, D.S. Puleo, B.J. Morgan, J.B. Skatrud."Cerebrovascular Response to CO2 in Patients with Congestive Heart Failure" /.
January 2004 A. Xie, R. Khayat, J.A. Dempsey, B. Chenuel, J.H. Lin, J.B. Skatrud."Effect of Cerebrovascular Reactivity to CO2 on the Hypercapnic Ventilatory Response" ..
September 2007 R . Khayat , B . Patt , T . Yamokoski , W . Abraham."Obstructive Sleep Apena May Play a Role in the Acute Decompensation of Heart Failure" /. : S172
January 2007 RN Khayat, D Jarjoura, B Patt, WT Abraham."Comparison between CPAP and BIPAP for the Treatment of OSA in Patients with Chronic Systolic Heart Failure" /.
January 2008 Rami N Khayat, Brian Patt, Roger Holt, Xiaoxue Fan, Min Pu."Beneficial Effects of Continuous Positive Airway Pressure on LV Diastolic Function in Patients with Congestive Heart Failure and Obstructive Sleep Apnea" ..
April 2008 R. N. Khayat, S. J. Schutzman, B. T, Patt, , S. Roy, G. Gordillo, R. Schlanger, L. Lambert, K. Rose, U. Gnyawali, A. Coston and C. K. Sen."Prevalence of Obstructive Sleep Apnea In Patients of an Academic Wound Center" /. : A10–A58
January 2008 B. Patt, R. N. Khayat, , S. Roy, G. Gordillo, R. Schlanger, L. Lambert, & C. K. Sen."Risk Factors and Role of Obstructive Sleep Apnea in Patients with Chronic Non-Healing Wounds" ..
June 2008 Rami Khayat, Brian Patt, Stephen Schutzman, David Jarjoura, and William Abraham."Role of Obstructive Sleep Apnea in the Acute Decompensation of Heart Failure" ..
June 2008 Brian Patt B.S. Jian Sun PhD , Jay Zweier MD , Arturo Cardounel PhD, Stephen Schutzman B.S., Rami Khayat MD."Endothelial Dysfunction in Obstructive Sleep Apnea and The Role of Endogenous Inhibitors Of Nitric Oxide" ..
June 2009 Haddad, D., Patt, B.,Yearsley, K., Khayat, R.."Oxidative Stress and Endothelial Dysfunction in Patients with Obstructive Sleep Apnea" /.
January 2009 Brian Patt, Lynn Lambert, Sashwati Roy, Gayle Gordillo, Richard Schlanger, & Chandan. K. Sen, Rami Khayat."Validation of Obstructive Sleep Apnea Screening of Patients in an Academic Wound Center" .
September 2009 Javaheri S, Goetting M, Khayat RN, Goodwin J, Wyle P."The ability of auto servo ventilation to eliminate complex central sleep apnea" Vienna.
May 2010 J. Wannemacher, B. Patt, R. Khayat."The Inflammatory Response in OSA and its Relation to Endothelial Dysfunction" New Orleans.
June 2010 Khayat RN, et al.."A Novel Approach Using Phrenic Nerve Stimulation to Treat Central Sleep Apnea: First-In-Man Experience" /.
January 2010 Ponikowski P, Zhang SJ, Witkowski T, Hasan A, Khayat RN, Bart B, Jagielski D, Zhang X."Central Sleep Apnea Events are Terminated by Phrenic Nerve Stimulations" .. : E289
May 2010 B. Patt, M. Powers, J. Wannemacher, R. Khayat."Central Sleep Apnea Predicts Post-Discharge Readmission in Patients with Decompensated Heart Failure" New Orleans.
November 2012 Varadharaj Jacob Wannemacher, Brian Patt, Hemalatha Rao, Levy Reyes, Jay L Zweier, Rami Khayat."S-glutathionylation of eNOS occurs in Clinical Obstructive Sleep Apnea (OSA)" Los Angeles.
November 2012 Saradhadevi Varadharaj Jacob Wannemacher, Brian Patt, Hemalatha Rao, Levy Reyes, Jay L Zweier, Rami Khayat."eNOS uncoupling leads to endothelial dysfunction in clinical Obstructive Sleep A pnea (OSA) : Role of BH4 depletion" Los Angeles.
September 2013 Angela Sow, Robert Dohar, Brittany Mantia, Matthew Lahman, William Abraham, Rami Khayat."Sleep Disordered Breathing as an Independent Predictor of Post-Discharge Mortality in Patients with Acutely Decompensated Heart Failure" Orlando.
September 2013 Angela Sow, Robert Dohar, Brittany Mantia, Matthew Lahman, William Abraham, Rami Khayat.."Sleep Disordered Breathing Is an Independent Predictor of One Month Readmission in Decompensated Heart Failure Hospitalizations" Orlando.
March 2013 Campbell, L, Best, J, Khayat, RN, Splaingard, M."Issues Applying a Math Model to Estimate Continuous Positive Airway Pressure Response in Cheyne-Stokes Respiration" /. : 553

Presentations

"Treatment of CHF-CSA." Presented at Wisconsin Thoracic Society Annual Meeting, . (January 2001)

"Thromboembolic Disease in the ICU." Presented at Tri-State Thoracic Society International Conference, . (January 2001)

"Pathophysiology and Treatment of Cheyne-Stokes Respiration." Presented at American Thoracic Society International Conference, San Diego, CA. (May 2001)

"The Neurocirculatory Consequences of Sleep Apnea." Presented at American Thoracic Society International Conference, . (May 2002)

"Weaning from Mechanical Ventilation." Presented at Annual Pulmonary and Critical care symposium, Columbus, OH. (November 2004)

"Strategies for Liberation from Mechanical Ventilation." Presented at MedNet 21 televised lecture series Critical Care Curriculum, Columbus, OH. (August 2005)

"Tight Glycemic Control in the Hospital Setting- A second look." Presented at The SELECT Medical Directors/CEO Annual Conference, Miami, FL. (March 2006)

"Practical Approach to Sleep Apnea and Heart Failure." Presented at Heart Failure Society of America, Seattle, WA. (September 2006)

"Sleep Related Breathing Disorders and the Heart." Presented at Medical Grand Rounds, Roanoke, VA. (May 2006)

"Endocrine issues in the ICU." Presented at SELECT Specialty Hospital, Washington, DC. (April 2007)

"The OSU Sleep Heart Program-a vital merger of two specialties." Presented at The American Association of Heart Failure Nurses Annual Meeting,, San Diego, CA. (June 2007)

"The Cardiovascular Consequences of Sleep Apnea." Presented at The Sleep Group, Houston, TX. (May 2007)

"Obstructive Sleep Apnea and Chronic Non-Healing Wounds." Presented at Annual Meeting of the National Wound Healing Society, San Diego, CA. (April 2008)

"Sleep and Sleepiness for the Artist." Presented at Workshop, Columbus, OH. (January 2008)

"Sleep Disordered Breathing in the Hospitalized Patient with Cardiovascular Disease." Presented at The Heart of it All-Annual Ross Hospital Nursing Conference, . (January 2008)

"The Cardiovascular Consequences of Obstructive Sleep Apnea." Presented at American College of Cardiology-Ohio Chapter Meeting, OH. (October 2009)

"Obstructive Sleep Apnea: Presentation and Management for the Respiratory Therapist." Presented at Current Concepts in Respiratory Care Conference, . (April 2009)

"Obstructive Sleep Apnea and Wound Healing - An Important Co-morbidity." Presented at Wound Care and HBO Update, . (April 2009)

"Healthy Hearts." Presented at Indiana Sleep Society, IN. (August 2009)

"Anemia in ICU." Presented at SELECT Annual Medical Director and CEO Meeting, Washington, DC. (April 2010)

"The Cardiovascular Complications of Obstructive Sleep Apnea." Presented at The 32nd Annual Ohio Society for Respiratory Care State Meeting, . (August 2010)

"Novel Approach to the Treatment of Central Sleep Apnea." Presented at The American Academy of Sleep Medicine Annual Meeting, . (June 2010)

"Sleep Disordered Breathing for the Respiratory Therapist." Presented at The 2010 Blue Ridge Symposium, Sleep Conference, Front Royal, VA. (September 2010)

"Obstructive Sleep Apnea: What does the primary care physician need to know?." Presented at CME Symposium, 2010 Update on Sleep Disorders, Madison, WI, US|USA. (September 2010)

"OSA and Cardiovasular Metabolic Risk." Presented at Lipid Update: Cardiometabolic Risk, . (February 2011)

"Sleep and Cardiovascular Diseases "Summit"." Presented at American College of Cardiology, . (December 2011)

"OSA in the Operating Room: Approach to patients with OSA in the pre-operative area." Presented at The Blue Ridge Symposium, Front Royal, VA. (September 2011)

"Sleep Disordered Breathing and Heart Failure." Presented at National Sleep Meeting, Keynote Symposium, Columbus, OH. (October 2011)

"Sleep Heart ACC summit." Presented at Sleep and Heart Summit; The American College of Cardiology, Washington, DC. (December 2011)

"The Cardiovascular Consequences of Sleep Apnea." Presented at Ohio Association of Advanced Practice Nurses: 22nd Annual Statewide Education Conference, . (November 2012)

"Detection and Diagnosis of Central Sleep Apnea." Presented at Heart Failure Society of America, Orlando, FL, US|USA. (September 2013)

"Sleep Disordered Breathing in Heart Failure: A Target for Improved Outcomes." Presented at Heart Failure Society of America, Orlando, FL, US|USA. (September 2013)

"Sleep Disordered Breathing: A Novel Target in the Management of Decompensated Heart Failure." Presented at Positive Airway pressure and Heart Failure 7th Annual Conference, Tokyo, JP|JPN. (February 2013)

"Sleep Disordered Breathing- Update on Diagnosis and Treatment." Presented at Special seminar, Keio Medical School, Tokyo, JP|JPN. (February 2013)

"Sleep Medicine, Speaker." Presented at International Brain and Heart Summit, . (November 2014)

"Thematic Poster Presentations on Outcomes of Sleep Disordered Breathing and Sleep Loss; Lead facilitator." Presented at American Thoracic Society, . (May 2015)

 

Professional Activities

2005 - present Consultant to Biomedical Company. Respironics, Inc.
2007 - present Consultant to Biomedical Company. Cardiac Concepts, Inc.
2007 - present Consultant to Biomedical Company. Widemed - GE, Israel.
2008 - present Davis Heart and Lung Research Institute Annual Research Retreat and Abstract Competition. Davis Heart and Lung Research Institute.
2010 - present Davis/Bremer Research Fund. OSU Center for Clinical and Translational Science.
2012 - present Reviewer. Population Health Science and Health Service Research Health Research Board, Republic of Ireland.
2013 - present Reviewer. NIH Pathway to Independence K99/K22 ZHL1 CSR-P.
2015 - present Special Emphasis Panel/Scientific Review Group 2015/05 ZHL1 CSR-I (M1). NIH.
2015 - present Lung Section. American Heart Association.
2015 - present reviewer. NIH Infectious Disease, Reproductive Health, and Asthma/Pulmonary Conditions (IRAP) study section.
2006 Student Research Scholarship Applications. Ohio State University.
2009 Reviewed Grands Submitted to the Foundation. Kentucky Science and Engineering Foundation Grant.
2009 - 2010 Student Research Scholarship Applications. Ohio State University.
2006 - 2012 Public and Patient Education. Net Wellness.